Access to quality harm reduction resources is genuinely life-saving for people who use substances. The following is a curated list of the most reliable, evidence-based harm reduction organizations, drug checking services, and emergency resources.
Crisis and Emergency Resources
Never Use Alone (US): 1-800-484-3731 — Call while using opioids alone. Operators will call 911 if you stop responding.
SAMHSA National Helpline: 1-800-662-4357 — Free, confidential, 24/7 treatment referral and information service.
Naloxone (Narcan) is available without prescription in most US states from pharmacies and NEXT Distro (by mail, free for eligible states).
Drug Information and Testing
DanceSafe: dancesafe.org — Drug checking reagent kits and fentanyl test strips. Extensive drug information library.
TripSit: tripsit.me — Real-time harm reduction chat and comprehensive drug combination safety database.
Erowid: erowid.org — Extensive documentation of substances, dosage information, pharmacology, and user experience reports.
The Loop (UK): wearetheloop.org — Drug checking services at UK events using FTIR spectrometry and GC-MS analysis.
For our complete harm reduction guide with drug-specific safety information, see the full guide.